Administration Routes

Forms

• Vape
• Smoke
• Floss
• Oil

• Capsule
• Oil
• Juicing
• Edibles

• Drops
• Spray
• Lozenge
• Wafer
• Tincture
• Oil

• Cream
• Gel
• Salve

Absorption

Lungs

Stomach and/or small intestine

Through oral mucosa into bloodstream

At external local application site

Bioavailability

• THC ~ 5-35%
• CBD ~ 31%
• Almost immediate

THC/CBD ~4-20% ~2-6 hrs after Ingestion

Studies of bioavailability not available

Studies of bioavailability not available

Onset

Rapid

90 mins

15-60 mins

unknown

Peak

30 mins

2-3 hrs

1-2 hrs

unknown

Duration

1-4 hrs

6-8 hrs

1-4 hrs

unknown

Comments

Vaping is recommended over smoking

Absorption impacted by stomach contents, carrier medium, type of capsule – some capsules designed to increase bioavailability

Important to hold under the tongue rather than swallow to increase absorption directly into blood stream

Can be used on rashes. Does not penetrate the deeper layers of the aqueous skin efficiently. Does not cause any ‘high’ related to THC.