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Medicinal Cannabis and Epilepsy

Medicinal Cannabis and Epilepsy Syndromes

Medicinal Cannabis Studies

Medicinal Cannabis in Australia

Cannabidiol reduces seizures and associated behavioral comorbidities in a range of animal seizure and epilepsy models

Patra PH, Barker-Haliski M, White HS, Whalley BJ, Glyn S, Sandhu H, Jones N, Bazelot M, Williams CM, McNeish AJ

Epilepsia Feb 2019 (Article)

Medicinal Cannabis and Epilepsy

Cannabis for refractory epilepsy in children: A review focusing on CDKL5 Deficiency Disorder

Dale T, Downs J, Olson H, Bergin AM, Smith S, Leonard H

Epilepsy Research Feb 2019 (Abstract)

Medicinal Cannabis and Epilepsy

Efficacy of cannabinoids in paediatric epilepsy

Ali S, Scheffer IE, Sadleir LG

Developmental Medicine & Child Neurology Jan 2019 (Abstract)

Medicinal Cannabis and Epilepsy

Therapeutic Use of medicinal cannabis in difficult to manage epilepsy

John A Lawson and Ingrid E Scheffer

British Journal of Clinical Pharmacology Nov 2018 (Article)

Medicinal Cannabis and Epilepsy

Efficacy and Safety of Cannabidiol in Epilepsy: A Systematic Review and Meta-Analysis

Lattanzi S, Brigo F, Trinka E, Zaccara G, Cagnetti C, Del Giovane C, Silvestrini M.

Drugs Nov 2018 (Abstract)

Medicinal Cannabis and Epilepsy

Long-term safety and treatment effects of cannabidiol in children and adults with treatment-resistant epilepsies: Expanded access program results

Szaflarski JP, Bebin EM, Comi AM, Patel AD, Joshi C, Checketts D, Beal JC, Laux LC, De Boer LM, Wong MH, Lopez M, Devinsky O, Lyons PD, Zentil PP and Wechsler R

Epilepsia Aug 2018 (Article)

Medicinal Cannabis and Epilepsy

Efficacy of CBD-enriched medical cannabis for treatment of refractory epilepsy in children and adolescents – an observational, longitudinal study

Hausman-Kedem M, Menascu S, Kramer U.

Brain and Development Aug 2018 (Abstract)

Medicinal Cannabis and Epilepsy

Composition and Use of Cannabis Extracts for Childhood Epilepsy in the Australian Community

A. Suraev, N. Lintzeris, J. Stuart, R. C. Kevin, R. Blackburn, E. Richards, J. C. Arnold, C. Ireland, L. Todd, D. J. Allsop & I. McGregor

Scientific Reports Jul 2018 (Article)

Medicinal Cannabis and Epilepsy

Cannabidiol exerts antiepileptic effects by restoring hippocampal interneuron functions in a temporal lobe epilepsy model

Khan AA, Shekh-Ahmad T, Khalil A, Walker MC, Ali AB.

British Journal of Pharmacology Jun 2018 (Abstract)

Medicinal Cannabis and Epilepsy

Evidence for cannabis and cannabinoids for epilepsy: a systematic review of controlled and observational evidence

Emily Stockings, Dino Zagic, Gabrielle Campbell, Megan Weier, Wayne D Hall, Suzanne Nielsen, Geoffrey K Herkes, Michael Farrell, Louisa Degenhardt

Journal of Neurology & Neurosurgical Psychiatry Mar 2018 (Article)

Medicinal Cannabis and Epilepsy

Cannabidiol Regulates Long Term Potentiation Following Status Epilepticus: Mediation by Calcium Stores and Serotonin

Maggio N, Stein ES, Segal M

Frontiers in Molecular Neuroscience Feb 2018 (Article)

Medicinal Cannabis and Epilepsy

The use of cannabidiol for seizure management in patients with brain tumor-related epilepsy

Warren PP, Bebin EM, Nabors LB, Szaflarski JP

Neurocase Oct 2017 (Abstract)

Medicinal Cannabis and Epilepsy

Interactions between cannabidiol and commonly used antiepileptic drugs

Gaston TE, Bebin EM, Cutter GR, Liu Y and Szaflarski JP

Epilepsia Sep 2017 (Article)

Medicinal Cannabis and Epilepsy

Quality of Life in Childhood Epilepsy in pediatric patients enrolled in a prospective, open-label clinical study with cannabidiol

Rosenberg EC, Louik J, Conway E, Devinsky O, Friedman D

Epilepsia Aug 2017 (Abstract)

Medicinal Cannabis and Epilepsy

Pharmacology of cannabinoids in the treatment of epilepsy

Gaston TE and Friedman D

Epilepsy & Behavior May 2017 (Abstract)

Medicinal Cannabis and Epilepsy

An Australian nationwide survey on medicinal cannabis use for epilepsy: History of antiepileptic drug treatment predicts medicinal cannabis use

Suraev AS, Todd L, Bowen MT, Allsop DJ, McGregor IS, Ireland C and Lintzeris N

Epilepsy & Behavior May 2017 (Article)

Medicinal Cannabis and Epilepsy

Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial

Devinsky O, Marsh E, Friedman D, Thiele E, Laux L, Sullivan J, Miller I, Flamini R, Wilfong A, Filloux F, Wong M, Tilton N, Bruno P, Bluvstein J, Hedlund J, Kamens R, Maclean J, Nangia S, Singhal NS, Wilson CA, Patel A, Cilio MR

The Lancet Neurology Mar 2016 (Abstract)

Medicinal Cannabis and Epilepsy

CBD-enriched medical cannabis for intractable pediatric epilepsy: the current Israeli experience

Tzadok M, Uliel-Siboni S, Linder I, Kramer U, Epstein O, Menascu S, et al.

Seizure Feb 2016 (Article)

Medicinal Cannabis and Epilepsy

Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy

Geffrey AL, Pollack SF, Bruno PL and Thiele EA

Epilepsia: Aug 2015 (Article)

Medicinal Cannabis and Epilepsy

Cannabidiol in patients with Lennox‐Gastaut syndrome: Interim analysis of an open‐label extension study

Thiele E, Marsh E, Mazurkiewicz‐Beldzinska M, Halford JJ, Gunning B, Devinsky O, Checketts D, Roberts C

Epilepsia Mar 2019 (Article)

Medicinal Cannabis and Epilepsy Syndromes

Efficacy and Safety of Adjunctive Cannabidiol in Patients with Lennox-Gastaut Syndrome: A Systematic Review and Meta-Analysis

Lattanzi S, Brigo F, Cagnetti C, Trinka E and Silvestrini M

CNS Drugs Oct 2018 (Abstract)

Medicinal Cannabis and Epilepsy Syndromes

Open-label use of highly purified CBD (Epidiolex®) in patients with CDKL5 deficiency disorder and Aicardi, Dup15q, and Doose syndromes

Devinsky O, Verducci C, Thiele EA, Laux LC, Patel AD, Filloux F, Szaflarski JP, Wilfong A, Clark GD, Park YD, Seltzer LE, Bebin EM, Flamini R, Wechsler RT and Friedman D

Epilepsy & Behavior Sep 2018 (Article)

Medicinal Cannabis and Epilepsy Syndromes

Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome

Devinsky O, Patel AD, Cross JH, Villanueva V, Wirrell EC, Privitera M, Greenwood SM, Roberts C, Checketts D, Van Landingham KE and Zuberi SM

New England Journal of Medicine May 2018 (Abstract)

Medicinal Cannabis and Epilepsy Syndromes

Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome

Devinsky O, Patel AD, Thiele EA, Wong MH, Appleton R, Harden CL, Greenwood S, Morrison G and Sommerville K

Neurology Apr 2018 (Article)

Medicinal Cannabis and Epilepsy Syndromes

Cannabidiol as a Potential Treatment for Febrile Infection-Related Epilepsy Syndrome (FIRES) in the Acute and Chronic Phases

Gofshteyn JS, Wilfong A, Devinsky O, Bluvstein J, Charuta J, Ciliberto MA, Laux L, Marsh ED

Journal of Child Neurology Aug 2017 (Abstract)

Medicinal Cannabis and Epilepsy Syndromes

Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome

Devinsky O, Cross JH, Laux L, Marsh E, Miller I, Nabbout R, Scheffer IE, Thiele EA and Wright S

New England Journal of Medicine May 2017 (Article)

Medicinal Cannabis and Epilepsy Syndromes

Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex

Hess EJ, Moody KA, Geffrey AL, Pollack SF, Skirvin LA, Bruno PL, Paolini JL and Thiele EA.

Epilepsia Oct 2016 (Article)

Medicinal Cannabis and Epilepsy Syndromes

Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder

Pretzsch CM, Freyberg J, Voinescu B, Lythgoe D, Horder J, Mendez MA, Wichers R, Ajram L, Ivin G, Heasman M, Edden RAE, Williams S, Murphy DGM, Daly E, McAlonan GM

Neuropsychopharmacology Feb 2019 (Abstract)

Medicinal Cannabis Studies

Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history

Bonini SA, Premoli M, Tambaro S, Kumar A, Maccarinelli G, Memo M, Mastinu A

Journal of Ethnopharmacology Dec 2018 (Abstract)

Medicinal Cannabis Studies

The Anti-Inflammatory Properties of Terpenoids from Cannabis

Gallily R, Yekhtin Z, Hanuš LO

Cannabis and Cannabinoid Research Dec 2018 (Article)

Medicinal Cannabis Studies

Cannabis, from plant to pill

Christopher P. L. Grof

British Journal of Clinical Pharmacology Nov 2018 (Article)

Medicinal Cannabis Studies

Cannabis contaminants: sources, distribution, human toxicity and pharmacologic effects

Laura M. Dryburgh, Nanthi S. Bolan, Christopher P.L. Grof, Peter Galettis, Jennifer Schneider, Catherine J. Lucas and Jennifer H. Martin

British Journal of Clinical Pharmacology Nov 2018 (Article)

Medicinal Cannabis Studies

Medical cannabis: aligning use to evidence‐based medicine approach

Lihi Bar‐Lev Schleider, Ran Abuhasira and Victor Novack

British Journal of Clinical Pharmacology Nov 2018 (Article)

Medicinal Cannabis Studies

The pharmacokinetics and the pharmacodynamics of cannabinoids

Catherine J. Lucas, Peter Galettis and Jennifer Schneider

British Journal of Clinical Pharmacology Nov 2018 (Article)

Medicinal Cannabis Studies

Cannabis Therapeutics and the Future of Neurology

Russo EB

Frontiers in Molecular Neuroscience Oct 2018 (Article)

Medicinal Cannabis Studies

Effectiveness of Raw, Natural Medical Cannabis Flower for Treating Insomnia under Naturalistic Conditions

Vigil JM, Stith SS, Diviant JP, Brockelman F, Keeling K, Hall B

Medicines Jul 2018 (Article)

Medicinal Cannabis Studies

Biphasic effects of THC in memory and cognition

Calabrese EJ, Rubio-Casillas A

European Journal of Clinical Investigation May 2018 (Abstract)

Medicinal Cannabis Studies

Practical considerations in medical cannabis administration and dosing

MacCallum CA, Russo EB

European Journal of Internal Medicine Mar 2018 (Article)

Medicinal Cannabis Studies

Pharmacogenetics of Cannabinoids

Hryhorowicz S, Walczak M, Zakerska-Banaszak O, Słomski R, Skrzypczak-Zielińska M

European Journal of Drug Metabolism and Pharmacokinets Feb 2018 (Article)

Medicinal Cannabis Studies

Delta-9-Tetrahydrocannabinol (∆9-THC) Induce Neurogenesis and Improve Cognitive Performances of Male Sprague Dawley Rats

Suliman NA, Taib CNM, Moklas MAM, Basir R

Neurotoxicity Research Feb 2018 (Article)

Medicinal Cannabis Studies

Tetrahydrocannabinolic acid (THCa) is a potent PPARγ agonist with neuroprotective activity

Xavier Nadal, Carmen del Río, Salvatore Casano, Belén Palomares, Carlos Ferreiro‐Vera, Carmen Navarrete, Carolina Sánchez‐Carnerero, Irene Cantarero, Maria Luz Bellido, Stefan Meyer, Gaetano Morello, Giovanni Appendino and Eduardo Muñoz

British Journal of Clinical Pharmacology Dec 2017 (Abstract)

Medicinal Cannabis Studies

Labeling Accuracy of Cannabidiol Extracts Sold Online

Marcel O. Bonn-Miller, Mallory J. E. Loflin, Brian F. Thomas, Jahan P. Marcu, Travis Hyke and Ryan Vandrey

JAMA Nov 2017 (Article)

Medicinal Cannabis Studies

Towards a better cannabis drug

Raphael Mechoulam and Linda Parker

British Journal of Clinical Pharmacology Dec 2013 (Article)

Medicinal Cannabis Studies

Survey of Australian psychiatrists’ and psychiatry trainees’ knowledge about and attitudes towards medicinal cannabinoids

Jacobs NI, Montebello M, Monds LA, Lintzeris N

Australasian Psychiatry Feb 2019 (Abstract)

Medicinal Cannabis in Australia

Medicinal cannabis in Australia,2016 : the Cannabis as Medicine Survey (CAMS-16)

Nicholas Lintzeris, Jessica Driels, Natalie Elias, Jonathon C Arnold, Iain S McGregor and David J Allsop

Medical Journal of Australia Sep 2018 (Article)

Medicinal Cannabis in Australia

Medicinal Cannabis and the Tyranny of Distance: Policy Reform Required for Optimizing Patient and Health System Net Benefit in Australia

David Caldicott, Justin Sinclair, Lynnaire Sheridan and Simon Eckermann

Applied Health Economics and Health Policy Apr 2018 (Article)

Medicinal Cannabis in Australia

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